Material Safety Data Sheet: 1-Chlorooctadecane

Identification

Product Name: 1-Chlorooctadecane
Chemical Formula: C18H37Cl
SYNONYM: Octadecyl chloride
CAS Number: 3386-33-2
Recommended Use: Research, chemical synthesis, intermediate
Supplier Details: Manufacturer or distributor address and contact number
Emergency Contact: Regional poison center or manufacturer emergency phone line

Hazard Identification

Classification: Irritant to skin and eyes, possible harmful effects if inhaled or swallowed
Signal Word: Warning
Hazard Symbols: Exclamation mark (GHS07)
Hazard Statements: Causes skin and eye irritation, may cause respiratory irritation, harmful if swallowed
Precautionary Statements: Wear protective gloves, avoid inhalation, wash hands thoroughly after handling, do not eat, drink, or smoke when using this chemical
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Symptoms: Redness, swelling, coughing, stomach upset, itchy skin, watering eyes

Composition / Information on Ingredients

Substance: Pure 1-Chlorooctadecane
Chemical Name: 1-Chlorooctadecane
Concentration: More than 99% by weight
Impurities: Long-chain alkyl chlorides may be present in trace levels
Molecular Weight: 289.94 g/mol
EINECS/ELINCS No: 222-207-1

First Aid Measures

Inhalation: Move person to fresh air, seek medical attention if breathing is difficult
Skin Contact: Wash with plenty of soap and water, remove contaminated clothing, get medical help if skin irritation occurs
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, call a physician if irritation persists
Ingestion: Rinse mouth, do not induce vomiting, get immediate medical assistance
Most Important Symptoms: Burning or rash on skin, respiratory discomfort, eye irritation
Advice for Doctors: Treat symptomatically, no specific antidote known

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, foam, carbon dioxide, sand
Unsuitable Extinguishing Media: Water jets (spillage spread risk)
Specific Hazards: Releases hazardous fumes (hydrogen chloride, phosgene, carbon monoxide) at high temperatures
Protection for Firefighters: Full protective gear, self-contained breathing apparatus
Additional Instructions: Stay upwind, cool exposed containers with water spray

Accidental Release Measures

Personal Precautions: Avoid inhalation and direct contact, ventilate area, wear appropriate PPE
Environmental Precautions: Prevent from entering sewers or watercourses
Spill Cleanup Methods: Absorb with inert material (sand, earth), collect in closed containers for disposal
Decontamination: Wash spill site thoroughly with soap and water once material removed

Handling and Storage

Handling: Work in well-ventilated space, wear gloves and eye protection, avoid aerosols or dust formation, do not eat or drink during handling
Storage Conditions: Store in tightly closed containers, cool dry place, away from heat sources and direct sunlight
Incompatibility: Strong oxidizers, strong acids, alkali metals
Packing Materials: Use corrosion-resistant and sealed containers

Exposure Controls and Personal Protection

Occupational Exposure Limits: Not established for 1-chlorooctadecane
Engineering Controls: Fume hood or local exhaust ventilation, eyewash station
Personal Protective Equipment: Chemical-resistant gloves, safety goggles, lab coat or coveralls, NIOSH-approved respirator if needed
Hygiene Measures: Wash hands after use, avoid skin and eye contact, remove contaminated clothing promptly

Physical and Chemical Properties

Appearance: White to pale yellow waxy solid
Odor: Mild, characteristic
Melting Point: 25–30°C (77–86°F)
Boiling Point: 187–190°C at 2 mmHg
Flash Point: >110°C (closed cup)
Vapor Pressure: Low at 20°C
Solubility: Insoluble in water, soluble in organic solvents (alcohols, chloroform, ether)
Density: 0.85–0.88 g/cm³ at 20°C
Viscosity: Not relevant for solid/waxy state
Partition Coefficient (log Kow): Estimated 8.5–10 (highly lipophilic)

Stability and Reactivity

Chemical Stability: Stable at ambient temperature and pressure
Conditions to Avoid: Heat, flame, strong sunlight
Materials to Avoid: Strong oxidizing agents, alkali metals
Hazardous Decomposition: Thermal decomposition may release hydrogen chloride, chlorine, carbon oxides, phosgene
Polymerization: Not expected under normal conditions

Toxicological Information

Acute Toxicity: Estimated low oral and dermal toxicity based on alkylchloride analogs (LD50 rat >2,000 mg/kg)
Skin Irritation: Causes mild to moderate irritation on contact
Eye Irritation: Irritating with redness and watering possible
Respiratory Effects: Vapors or mists can irritate throat and lungs
Chronic Exposure: Prolonged skin contact can lead to dermatitis
Sensitization: Not classified as sensitizer, some data gaps
Mutagenicity/Carcinogenicity: Not classifiable due to limited data and no IARC listing

Ecological Information

Aquatic Toxicity: Expected to be toxic to aquatic organisms due to bioaccumulation
Persistence and Degradability: Not readily biodegradable, may persist in environment
Bioaccumulation Potential: High due to very high log Kow, risk of buildup in aquatic food chains
Mobility in Soil: Strongly adsorbed to soil, limited groundwater mobility
Other Effects: No data on ozone depletion or global warming potential

Disposal Considerations

Waste Handling: Treat as hazardous waste, use licensed incineration or landfill
Disposal Containers: Chemically resistant and tightly sealed barrels
Regulatory Requirements: Follow local, state, national hazardous waste guidelines
Contaminated Packaging: Dispose as hazardous waste, do not reuse for food or feed

Transport Information

UN Number: Not classified under UN Dangerous Goods
Transport Hazard Class: Not a regulated class, check for local restrictions as harmful substance
Packing Group: Not assigned
Labeling Requirements: Ensure outer container clearly labeled with chemical name and hazard information
Proper Shipping Name: 1-Chlorooctadecane
Special Precautions: Avoid leaking containers, maintain integrity of outer packaging

Regulatory Information

TSCA: Listed on the US Toxic Substances Control Act Inventory
REACH Status: May need registration under EU chemical regulations
US OSHA: Covered as hazardous based on irritant properties
Canadian DSL/NDSL: Present or pending
Other Regulatory Listings: May appear on state right-to-know lists or international inventories
Label Requirements: Hazard pictograms, risk phrases, safety statements