Material Safety Data Sheet (MSDS) – 1-Bromopentane

Identification

Product Name: 1-Bromopentane
SYNONYMS: n-Pentyl bromide, Pentyl bromide
CAS NUMBER: 110-53-2
Recommended Use: Laboratory chemicals, organic synthesis
Manufacturer: Reach out to chemical supplier for details
Emergency Telephone: Refer to local and national emergency contact numbers

Hazard Identification

Classification: Flammable liquid, Acute toxicity (oral, dermal, inhalation), Skin irritation, Eye irritation, Specific target organ toxicity (single exposure)
Signal Word: Danger
Hazard Statements: Causes skin irritation, may cause respiratory irritation, harmful if swallowed/in contact with skin/inhaled, causes serious eye irritation, flammable liquid and vapor
Pictograms: Flame, Exclamation mark
Precautionary Statements: Avoid breathing fumes, keep away from open flames, wash hands thoroughly after handling, wear protective gloves and eye/face protection, use only outdoors or in well-ventilated area

Composition / Information on Ingredients

Chemical Name: 1-Bromopentane
Formula: C5H11Br
Molecular Weight: 151.05 g/mol
Concentration: 98–100%
Impurities: Trace alkyl bromides or unidentified impurities may be present in very low amounts

First Aid Measures

General Advice: Get immediate medical attention if symptoms develop
Inhalation: Move victim to fresh air, monitor breathing, seek medical help if discomfort continues
Skin Contact: Remove contaminated clothing, flush skin with large quantities of water for at least 15 minutes, wash with soap, get medical assistance if irritation persists
Eye Contact: Rinse eyes with plenty of water for at least 15 minutes lifting upper and lower eyelids occasionally, seek prompt medical attention
Ingestion: Rinse mouth with water, do not induce vomiting, never give anything by mouth to an unconscious person, call poison control and seek emergency care

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or foam
Specific Hazards Arising from Chemical: Toxic and irritating fumes (hydrogen bromide, bromine, carbon oxides) may be released
Protective Equipment for Firefighters: Self-contained breathing apparatus and full protective gear
Special Precautions: Move containers from fire area if it can be done safely, avoid exposure to vapors or decomposition products

Accidental Release Measures

Personal Precautions: Evacuate unnecessary personnel, ventilate area, use personal protective equipment, avoid contact with skin, eyes, clothing, and inhalation of vapors
Environmental Precautions: Prevent further leakage or spillage if safe to do so, do not let product enter drains, avoid release into environment
Methods for Clean Up: Absorb spill using inert materials like sand or vermiculite, place in chemical waste container for disposal, decontaminate spill area

Handling and Storage

Handling: Handle in well-ventilated areas, avoid breathing dust, vapor or mist, keep away from heat, sparks and open flame, use appropriate PPE
Storage: Store in tightly closed containers, keep in a cool, dry, well-ventilated location away from incompatible materials like strong oxidizers, acids and bases, store separately from food and feed products

Exposure Controls and Personal Protection

Engineering Controls: Use chemical fume hood, local exhaust, or adequate ventilation
Personal Protective Equipment: Chemical-resistant gloves (nitrile recommended), safety goggles, lab coat, flame retardant clothing if risk of ignition
Respiratory Protection: NIOSH-approved respirator required when exposure limits are exceeded or if ventilation is inadequate
Hygiene Measures: Wash hands before eating, drinking, or smoking, remove contaminated clothing and wash before reuse

Physical and Chemical Properties

Appearance: Colorless to pale yellow liquid
Odor: Characteristic sweet odor
Boiling Point: 129–131°C
Melting Point: –92°C
Flash Point: 34°C (closed cup)
Auto-ignition Temperature: 220°C
Vapor Pressure: 9.9 mmHg at 25°C
Solubility: Slightly soluble in water, soluble in most organic solvents
Density: 1.217 g/cm³ at 20°C
Viscosity: Not established
pH: Not applicable

Stability and Reactivity

Stability: Stable under normal temperatures and pressures
Reactivity: Reacts with strong oxidizers, bases, and alkali metals
Hazardous Decomposition: Hydrogen bromide, carbon oxides, bromine gas
Conditions to Avoid: Heat, flames, sparks, strong alkalis, oxidizing agents
Polymerization: Does not polymerize under normal conditions

Toxicological Information

Acute Toxicity: LD50 (oral, rat): 2500 mg/kg; inhalation may cause irritation to respiratory tract, headache, drowsiness, nausea
Chronic Effects: Prolonged exposure can affect central nervous system, liver, and kidneys
Skin Corrosion/Irritation: Causes moderate irritation on contact
Eye Damage/Irritation: Causes significant eye irritation and possible injury
Sensitization: Not expected to cause sensitization from normal handling
Carcinogenicity: Not classified as carcinogen by ACGIH, IARC, NTP, OSHA
Mutagenicity: Data not sufficient for determination
Reproductive Toxicity: Data not sufficient for determination

Ecological Information

Toxicity to Aquatic Life: Harmful to aquatic organisms, may cause long-term adverse effects in aquatic environment
Mobility: Expected to have moderate mobility in soils, unlikely to bioaccumulate significantly
Persistence and Degradability: Not readily biodegradable
Bioaccumulative Potential: Bioaccumulation not expected to be significant
Other Adverse Effects: No specific data, but avoid uncontrolled release into surface waters

Disposal Considerations

Waste Disposal Methods: Dispose of as hazardous waste following local, state, and federal regulations, incineration recommended where permitted
Contaminated Packaging: Triple rinse empty containers before disposal or recycling, puncture and dispose of in approved landfill if incineration is unavailable
Precautions: Do not discharge into drains, soil, or water bodies

Transport Information

UN Number: 1268
Shipping Name: Petroleum distillates, n.o.s. (contains 1-Bromopentane)
Transport Hazard Class: 3 (Flammable liquids)
Packing Group: III
Labels Required: Flammable liquid
Marine Pollutant: Yes (consult specific regulations)
Special Transport Notes: Ensure containers are secured against movement, comply with international, national, and local transport regulations

Regulatory Information

U.S. TSCA Inventory: Listed
OSHA Status: Classified as hazardous
SARA 313: Not subject to reporting
State Regulations: Check for state-specific regulations governing handling and disposal
REACH Registration: If imported into EU, subject to REACH
WHMIS Classification (Canada): Class B, Division 2: Flammable liquid; Class D, Division 2B: Toxic material
Other International Regulations: Listed in relevant chemical inventories in major jurisdictions; observe all applicable regional, national, and local laws