Material Safety Data Sheet: 1-Bromobutane

Identification

Product Name: 1-Bromobutane
Chemical Formula: C4H9Br
Synonyms: n-Butyl bromide, Butyl bromide
CAS Number: 109-65-9
Recommended Use: Organic synthesis, laboratory reagent, solvent
Manufacturer Information: Contact supplier or manufacturer for address and emergency numbers
Emergency Contact: Refer to local, national, or international emergency contacts for chemical exposures

Hazard Identification

Classification: Flammable liquids (Category 3), Acute toxicity (inhalation, dermal, oral), Skin and eye irritation, Specific target organ toxicity
Signal Word: Warning
Hazard Statements: Flammable liquid and vapor, harmful in contact with skin or if inhaled, causes skin and eye irritation, may cause drowsiness or dizziness
Precautionary Statements: Avoid breathing vapors, keep away from heat, sparks, open flames, use only in ventilated areas, wear protective clothing
Potential Health Effects: Inhalation can lead to respiratory irritation, dizziness, headache; skin exposure leads to redness and irritation

Composition / Information on Ingredients

Chemical Name: 1-Bromobutane
Concentration: 99% or higher
Impurities: May include traces of related brominated hydrocarbons or unreacted alcohols
Other Ingredients: No known stabilizers or additives used in standard supply

First Aid Measures

Inhalation: Move to fresh air, support breathing, keep individual calm and warm, administer oxygen if available, seek prompt medical attention
Skin Contact: Remove contaminated clothing and shoes, wash affected skin thoroughly with soap and water for at least 15 minutes, seek medical care for persistent irritation
Eye Contact: Rinse immediately with large amounts of water for at least 15 minutes, lift eyelids to ensure thorough washing, seek medical attention
Ingestion: Rinse mouth if conscious, never induce vomiting, offer water to dilute, get immediate medical help

Fire-Fighting Measures

Suitable Extinguishing Media: Use dry chemical, carbon dioxide, foam, or water spray for large fires
Unsuitable Media: High-pressure water streams may spread the fire
Special Protective Equipment for Firefighters: Wear positive pressure SCBA and full protective gear, avoid inhaling combustion gases
Hazardous Combustion Products: Releases hydrogen bromide, carbon monoxide, carbon dioxide, and other toxic fumes
Fire Hazards: Vapors can form explosive mixtures in air, runoff can cause fire spread, containers may rupture from pressure when exposed to heat

Accidental Release Measures

Personal Precautions: Evacuate non-essential personnel, ventilate area, avoid breathing vapors, use chemical protective gloves and goggles
Environmental Precautions: Prevent entry into drains, waterways, or soil, alert authorities if spill occurs in natural environment
Methods and Materials for Cleanup: Absorb with inert materials like sand or earth, collect using non-sparking tools, place in suitable closed containers for disposal, ventilate spill area after cleanup

Handling and Storage

Handling: Use with local exhaust or good general ventilation, ground containers when dispensing, keep away from sources of ignition, avoid static charge buildup, do not breathe vapor, minimize contact
Storage: Store in tightly closed containers, in cool, dry, well-ventilated areas away from sunlight and incompatible substances such as strong oxidizers and acids, segregate from food and feeds
Special Storage Precautions: Protect from physical damage, check for leaks regularly, store below 25°C to minimize vapor formation

Exposure Controls and Personal Protection

Occupational Exposure Limits: No OSHA PEL or ACGIH TLV for 1-Bromobutane; use general vapor limits as guideline
Engineering Controls: Use chemical fume hoods, explosion-proof ventilation systems, local exhaust where necessary
Personal Protective Equipment: Wear chemical-resistant gloves (butyl rubber or nitrile), safety goggles or face shield, flame-resistant lab coat or apron, use respiratory protection in poorly ventilated areas
Hygiene Measures: Wash hands after handling, launder contaminated clothing before reuse, keep food and drink away from work area

Physical and Chemical Properties

Appearance: Clear, colorless liquid
Odor: Characteristic sweet odor
Molecular Weight: 137.02 g/mol
Boiling Point: 101-104°C (214-219°F)
Melting Point: -112.2°C (-170°F)
Flash Point: 23°C (73.4°F) (Closed cup)
Flammability: Burns with difficulty, forms flammable vapor-air mixtures
Vapor Pressure: 18 mmHg at 20°C
Solubility: Slightly soluble in water, mixes well with alcohol, ether, and chloroform
Specific Gravity: 1.27 at 20°C
Partition Coefficient (log Pow): 2.93
Autoignition Temperature: 235°C (455°F)

Stability and Reactivity

Chemical Stability: Stable under recommended handling and storage conditions
Reactivity: Can react vigorously with strong oxidizers, strong bases, and some metals
Hazardous Decomposition: Produces toxic gases such as hydrogen bromide and carbon oxides if heated or burned
Polymerization: Not known to polymerize under normal conditions
Conditions to Avoid: Exposure to heat, flames, sparks, and incompatible substances such as strong bases and oxidizers

Toxicological Information

Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Acute Toxicity: Oral LD50 (rat): 3,173 mg/kg; Dermal LD50 (rabbit): 4,000 mg/kg; Inhalation LC50 (rat): 17 mg/L (4 hours)
Symptoms of Overexposure: Nausea, headache, dizziness, central nervous system depression, skin and eye irritation
Sensitization: No data available on allergic sensitization
Chronic Effects: Extended exposure may affect liver, kidneys, nervous system, or respiratory system

Ecological Information

Aquatic Toxicity: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Bioaccumulation Potential: Moderate (log Kow 2.93), can accumulate in aquatic organisms
Degradability: Not readily biodegradable in the environment, persists for an extended period
Soil Mobility: Low; potential for leaching into groundwater if released in large quantities

Disposal Considerations

Waste Disposal: Place in closed and labeled chemical waste containers, dispose at a licensed facility, do not pour down drains or onto land
Contaminated Packaging: Must be disposed as hazardous waste, triple rinse before disposal if not being recycled

Transport Information

UN Number: 1126
UN Proper Shipping Name: 1-Bromobutane
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: III
Environmental Hazards: Marine pollutant (IMDG)
Special Precautions: Keep containers tightly closed, store and transport in upright position, protect from direct sunlight and incompatible materials

Regulatory Information

Labeling Requirements: Complies with OSHA GHS labeling, includes flame, exclamation mark signal pictograms
TSCA Status: Listed on U.S. Toxic Substances Control Act inventory
Hazard Categories: Fire hazard, acute health hazard
Other Regulations: Subject to workplace safety regulations in Europe (REACH), Canada (WHMIS), and globally; check local, state, and national rules for storage and transport