Material Safety Data Sheet for 1,6-Dichlorohexane

Identification

Product Name: 1,6-Dichlorohexane
Chemical Formula: C6H12Cl2
Synonyms: Hexamethylene dichloride, 1,6-Dichlorhexan, Dichlorohexane
CAS Number: 2163-00-0
Recommended Use: Intermediate in organic synthesis, research, manufacturing of specialty chemicals
Manufacturer: Information from supplier or manufacturer required for emergency contacts and further guidance
Emergency Contact: Local poison control center or manufacturer emergency number

Hazard Identification

GHS Classification: Skin irritation (Category 2), Eye irritation (Category 2A), Specific target organ toxicity
Hazard Statements: Causes skin and eye irritation, may cause respiratory tract irritation, toxic to aquatic life
Pictograms: Corrosion, Exclamation mark, Environmental hazard
Signal Word: Warning
Precautionary Statements: Avoid breathing vapors, wash hands thoroughly after handling, avoid release to environment, wear protective gloves, eye protection, and face protection

Composition / Information on Ingredients

Chemical Name: 1,6-Dichlorohexane
Concentration: ≥98%
Impurities: Trace organic or inorganic compounds, managed by supplier quality controls
Molecular Weight: 155.06 g/mol
Other Components: No other hazardous ingredients present at reportable quantities

First Aid Measures

Inhalation: Move person to fresh air, support breathing with oxygen if necessary, consult physician
Skin Contact: Remove contaminated clothing, wash skin with plenty of soap and water, seek medical attention if irritation persists
Eye Contact: Rinse eyes cautiously with water for several minutes, remove contact lenses if present, continue rinsing, seek immediate medical advice
Ingestion: Rinse mouth thoroughly, do not induce vomiting, seek immediate medical care
Symptoms: Redness, pain, irritation to eyes and skin, respiratory issues after inhalation of vapors

Fire-Fighting Measures

Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, alcohol-resistant foam
Unsuitable Extinguishing Media: Water jets may spread product, not recommended for large volumes
Hazardous Combustion Products: Hydrogen chloride, phosgene, carbon oxides
Protective Equipment for Firefighters: Self-contained breathing apparatus, chemical protective clothing
Special Precautions: Cool exposed containers with water spray, isolate hazard area, prevent runoff from fire control from entering drains or waterways

Accidental Release Measures

Personal Precautions: Evacuate area, avoid breathing vapors, ensure adequate ventilation, wear suitable protective equipment
Environmental Precautions: Prevent further leakage or spillage if safe to do so, avoid discharge into drains, ditches, or watercourses
Methods for Containment: Dike and absorb spills with inert material like sand, collect in containers for disposal following local regulations
Cleanup Procedures: Use non-sparking tools, ventilate area, wash area after material pickup, dispose of contaminated cleaning materials appropriately

Handling and Storage

Safe Handling: Use only with adequate ventilation, avoid inhalation of vapors, prevent skin and eye contact, ground and bond containers, use explosion proof equipment
Storage Conditions: Keep tightly closed in a cool, dry, well-ventilated place, away from heat or sources of ignition, store separately from oxidizing agents and acids
Incompatible Materials: Strong oxidizers, acids, alkali metals
Container Requirements: Store in corrosion-resistant containers with resistant inner liners

Exposure Controls and Personal Protection

Occupational Exposure Limits: No specific limits set in ACGIH or OSHA; minimize exposures as recommended for hazardous solvents
Engineering Controls: Local exhaust ventilation, process enclosures
Respiratory Protection: Approved respirator if vapor concentrations exceed recommended threshold limits
Skin Protection: Chemical-resistant gloves (nitrile recommended), protective clothing
Eye Protection: Chemical splash goggles and face shield
Hygiene Measures: Immediately remove contaminated clothing, wash hands before eating, keep work area clean

Physical and Chemical Properties

Appearance: Colorless liquid
Odor: Mild, characteristic
Odor Threshold: Data not available
pH: Not applicable
Melting Point/Freezing Point: -10°C
Boiling Point/Range: 215-217°C
Flash Point: 93°C (closed cup)
Evaporation Rate: Data not available
Flammability: Not highly flammable, but combustible under certain conditions
Vapor Pressure: Low (<1 mmHg at 20°C)
Vapor Density: Heavier than air
Relative Density: 1.08 (water=1)
Solubility: Insoluble in water, miscible with organic solvents
Partition Coefficient (n-octanol/water): Log Kow ~4.2
Auto-ignition Temperature: >200°C
Decomposition Temperature: Data not available
Viscosity: Data not available

Stability and Reactivity

Chemical Stability: Stable under recommended handling and storage conditions
Reactivity: Reacts with strong oxidizers and bases
Hazardous Reactions: Violent reaction possible with incompatible substances
Decomposition Products: Hydrogen chloride, phosgene, carbon monoxide and dioxide
Conditions to Avoid: Heating, flames, sparks, incompatibles

Toxicological Information

Acute Toxicity: Oral LD50 (rat) estimated at >2,000 mg/kg, inhalation LC50 not well defined
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Symptoms: Irritation of respiratory tract, skin, eyes, possible nausea, dizziness
Chronic Effects: Prolonged or repeated exposure may cause skin dryness, dermatitis
Sensitization: Not reported
Carcinogenicity: Not classified by IARC, NTP, or OSHA
Mutagenicity: No clear studies
Reproductive Toxicity: No data available on significant reproductive hazards

Ecological Information

Toxicity to Aquatic Life: Harmful to aquatic organisms, long-term adverse effects likely
Persistence and Degradability: Not readily biodegradable in the environment
Bioaccumulative Potential: High potential for bioaccumulation (Log Kow >4)
Mobility in Soil: Low - likely to persist in the environment
Other Environmental Effects: Avoid release to waterways and natural habitats

Disposal Considerations

Waste Treatment Methods: Dispose of in accordance with local, regional, and national regulations using a licensed chemical waste contractor
Incineration: Recommended for controlled high temperature combustion
Container Disposal: Triple rinse, puncture, and offer containers for recycling, if appropriate; never reuse for food or drink
Hazardous Waste Codes: Follow applicable hazardous waste codes under RCRA or regional frameworks

Transport Information

UN Number: 2810
Proper Shipping Name: Toxic Liquid, Organic, N.O.S. (contains 1,6-Dichlorohexane)
Hazard Class: 6.1 (Toxic Substances)
Packing Group: III
Labels: Toxic substance, avoid contact and inhalation
Transport Regulations: Subject to DOT, IMDG, and IATA guidelines for hazardous materials
Special Precautions: Ensure secure and upright transport, use sealed and chemically resistant containers

Regulatory Information

OSHA Hazards: Irritant
SARA Section 313: Not listed
TSCA (Toxic Substances Control Act): Listed
EINECS/ELINCS: 218-473-5
REACH Authorization: Not subject to authorization
Canadian WHMIS Classification: D2B (Toxic Material Causing Other Toxic Effects)
Other National Regulations: Refer to national and local chemical safety regulations for storage, handling, and disposal